Ostase® BAP EIA

Product Description

The Ostase® BAP EIA Assay is an in-vitro device indicated for the quantitative measurement of bone-specific alkaline phosphatase (BAP), an indicator of osteoblastic activity in human serum1,2.

This device is intended to be used as an aid in the management of postmenopausal osteoporosis and Paget’s disease.

Ostase® is a registered trademark of Hybritech Incorporated, a subsidiary of Beckman Coulter, Inc.

Key Features and Values

Unique Features

  • Fast turnaround time – results in approximately half the time of other manual assays. (1h 15 mins. total incubation with <30 mins. hands-on time)
  • Measures bone specific alkaline phosphatase (BAP) with low interference from other alkaline phosphatase isoforms
  • Excellent limit of detection (<1.0 μg/L)
  • Clinically relevant assay range – accommodates samples in a wide dynamic range (7-90 μg/L)
  • Excellent correlation with automated methods
  • Complementary – ideal companion product to Immunodiagnostic Systems Limited continually growing bone marker range
  • A complete assay panel supporting bone disease management

Scientific Description

Serum levels of BAP are believed to reflect the metabolic status of osteoblasts. An accurate assessment of bone metabolism is critical for determining the severity of metabolic bone disease and responses to therapy.

Measurement of serum levels of BAP has been shown to be useful in evaluating patients with Paget’s disease, osteomalacia, primary hyperparathyroidism, renal osteodystrophy, osteoporosis and metastases to bone.

Complementary Products



Cavalier E et al., Inter-method variability in bone alkaline phosphatase measurement: Clinical impact on the management of dialysis patients. Clin Biochem. 2014 Sep;47(13-14):1227-30.

Raisz L et al., Comparison of the effects of oestrogen alone and oestrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women. J Clin Endocrin Metab. 1996; 81:37-43.

Product Code: AC-20F1

CE Marked
FDA Cleared

Clinical Area: Bone Turnover Markers (Endocrinology)
Type: Manual
Format: EIA
Number of Tests: 96 (40 samples in duplicate)
Sample Type: Serum
Sample Volume: 50 μL
Assay Range: 7-90 μg/L

Need more information? Get in touch

Fill in the boxes below to get in contact